The role of stem cells in hair regeneration

doi:10.3877/cma.j.issn.2095-1221.2022.02.008

Abstract

Abstract:

Owing to the fast-paced and stressful nature of modern life, an increasing number of people suffer from pathological hair loss. Throughout the current available therapies for hair loss, there are still multiple challenges, such as drug efficacy, side effects, patients' compliance, unfavorable outcomes of follicular transplantation and some unpredictable effects that may restrict its application. Recently, remarkable advances in the fields of regenerative medicine and hair tissue engineering have offered a new hope for hair loss therapies. To date, stem cell-based therapy approaches can be divided into three categories: stem cell transplantation, stem cell-derived conditioned medium and stem cell-derived exosomes. We focus on reviewing recent advances in alopecia treatment using stem cell-based approaches.

Key words: Hair follicle, Stem cell, Hair follicle transplantation, Hair loss

Yingying Yang, Bo Diao, Yueping Liu, Qian Yang, Chuancheng Zhang, Gang Wang. The role of stem cells in hair regeneration[J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2022, 12(02): 110-114.

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