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Chinese Journal of Cell and Stem Cell(Electronic Edition) ›› 2017, Vol. 07 ›› Issue (03): 178-184. doi: 10.3877/cma.j.issn.2095-1221.2017.03.011

Special Issue:

• Review • Previous Articles     Next Articles

Repairing cartilage injury using mesenchymal stem cells: a literature review

Xudong Wei1, Yuan Dang1, Deqing Hu2,()   

  1. 1. Bengbu Medical College, Affiliated Fuzhou general Hospital of Nanjing Command, People's Liberation Army of China, Fuzhou 350025, China
    2. Department of Orthopedics, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China
  • Received:2017-04-18 Online:2017-06-01 Published:2017-06-01
  • Contact: Deqing Hu
  • About author:
    Corresponding author: Hu Deqing, Email:

Abstract:

Incidence rate of articular cartilage injury is increasing. As cartilage is a highly differentiated tissue without direct supply of blood or nerve and has limited regeneration potential after injury, treatment of cartilage injury still poses a major challenge for both patients and orthopedic surgeons. Mesenchymal stem cells (MSCs) are a class of pluripotent stem cells with potent proliferative capacity and chondrogenic ability, and are being used to repair articular cartilage injury through tissue engineering. The aim of this article is to provide a comprehensive review of MSC transplantation for the treatment of articular cartilage injury.

Key words: Cartilage, Repair, Mesenchymal stem cells, Tissue engineering

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