Mechanism and research progress of human umbilical cord mesenchymal stem cells in treating nervous system diseases

doi:10.3877/cma.j.issn.2095-1221.2025.06.007

Abstract

Abstract:

Human umbilical cord mesenchymal stem cells (hUC-MSCs) have shown significant potential in the field of neural injury repair due to their high proliferation capacity, low immunogenicity and easy accessibility. It has been demonstrated that hUC-MSCs can effectively attenuate neural functional damage through multiple pathways, such as promoting neural differentiation, exerting paracrine effects and regulating the immune microenvironment. This article aims to review the latest research progress and potential mechanisms of hUC-MSCs in the treatment of neurological diseases, and to prospect their future clinical application prospects, providing new ideas for the development of neural regenerative medicine.

Key words: Human umbilical cord mesenchymal stem cells, Nervous system disease, Therapeutic mechanism

Lili Liu, Wei Wang, Zhihua Zhang. Mechanism and research progress of human umbilical cord mesenchymal stem cells in treating nervous system diseases[J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2025, 15(06): 368-373.

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