Advances in the potential repairment of novel coronavirus-induced immune injury by mesenchymal stem cells

doi:10.3877/cma.j.issn.2095-1221.2020.04.006

Abstract

Abstract:

In response to the sweep of new coronaviruses and the absence of special drug treatments, many places have seen clinical research on mesenchymal stem cells (MSCs) in the treatment of severe infections of new coronaviruses. Based on standardized procedures and rigidclinical examinations, severe cases of the new coronavirus disease were treated with certain effects. MSCs could suppress the excessive activation of the immune system, and relieve respiratory distress by promoting endogenous repair and inhibiting pulmonary inflammation based on microenvironment improvement. This article introduces the pathogenetic mechanism and present status of treatment of new coronavirus-related immune injury, as well as the potential therapeutic mechanism of MSCs for new coronavirus infection.

Key words: COVID-19, Immune injury, Immune regulation, Mesenchymal stem cells

Ruiqi Ma, Tao Wu, Xiuhua Zhao, Jiucong Zhang, Xiaohui Yu, Qian Zhang. Advances in the potential repairment of novel coronavirus-induced immune injury by mesenchymal stem cells[J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2020, 10(04): 229-233.

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URL: https://zhxbygxbzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-1221.2020.04.006

https://zhxbygxbzz.cma-cmc.com.cn/EN/Y2020/V10/I04/229

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