Progress of immune regulatory function of Amniotic mesenchymal stem cells

doi:10.3877/cma.j.issn.2095-1221.2017.05.011

Abstract

Abstract:

The amniotic mesenchymal stem cell is a stem cell derived from the amnion. Compared with other sources of stem cells, the amniotic mesenchymal stem cell possesses the characteristics of low immunogenicity and immunosuppression, for which makes the side effect of transplantation of the amniotic mesenchymal stem cell relatively smaller. The efficient effects of the treatment have been shown in some diseases, which are associated with inflammation. Relevant clinical trials were carried out. Although some of the mechanisms of immunomodulation of amniotic mesenchymal stem cell has been found, but they are not completely clarified. This review outlines the immune regulatory function of the amniotic mesenchymal stem cell, which provides some information for the further studies.

Key words: Amniotic mesenchymal stem cell, Immunomodulation, Macrophage, T cell, Dendritic cell

Wen Ouyang, Zhengquan Liao, Zengfei Xia, Ya Gaoa, Yanwu Guo, Haitao Sun. Progress of immune regulatory function of Amniotic mesenchymal stem cells[J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2017, 07(05): 313-316.

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https://zhxbygxbzz.cma-cmc.com.cn/EN/Y2017/V07/I05/313

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