Research progress in members of lymphocyte subsets

doi:10.3877/cma.j.issn.2095-1221.2017.03.009

Abstract

Abstract:

Lymphocytes are very important immune cells in the body, accounting for 20﹪ ~ 45﹪ of peripheral leukocytes. The three major subpopulation of lymphocytes are T cells, B cells and NK cells. According to different surface markers and functional characteristics, lymphocytes are mainly divided into CD3⁺ CD4⁺ helper T cells, CD3⁺ CD8⁺ cytotoxic T cells, CD19⁺ B cells and CD16⁺ CD56⁺ NK cells. With the development of basic immunology and immunological techniques, new lymphocyte subsets are proposed, including gamma delta T cells, Th1/Th2 cells, Th17 cells, Th9 cells, Tfh cells, Treg cells, Breg cells, NKT cells, NKB cells, etc.The definition of lymphocyte subsets are refined constantly. The present review summarizes recent research progress of lymphocyte subsets.

Key words: T lymphocyte subsets, B lymphocyte subsets, Killer cells, natural, Lymphocyte subsets

Xihui Ma, Li Xiao. Research progress in members of lymphocyte subsets[J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2017, 07(03): 168-172.

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References 42

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成员	淋巴细胞亚群类别	淋巴细胞亚群的细分	淋巴细胞特殊亚群
T细胞	CD4⁺ T细胞（Th）	γδ T细胞	NKT细胞
	CD8⁺ T细胞（Tc）	αβ T细胞（Th、Tc）
		Th（Th1/Th2/Th17/Tfh/Treg/Th9/Th22）
		Tc（另CD8⁺ Treg、DNT）
B细胞	CD3^- CD19⁺ B细胞	B1、B2、另Breg	NKB细胞
NK细胞	CD3^- CD16⁺ CD56⁺	CD56 dim NK细胞
	NK细胞	CD56 bright NK细胞

成员	淋巴细胞亚群类别	淋巴细胞亚群的细分	淋巴细胞特殊亚群
T细胞	CD4⁺ T细胞（Th）	γδ T细胞	NKT细胞
	CD8⁺ T细胞（Tc）	αβ T细胞（Th、Tc）
		Th（Th1/Th2/Th17/Tfh/Treg/Th9/Th22）
		Tc（另CD8⁺ Treg、DNT）
B细胞	CD3^- CD19⁺ B细胞	B1、B2、另Breg	NKB细胞
NK细胞	CD3^- CD16⁺ CD56⁺	CD56 dim NK细胞
	NK细胞	CD56 bright NK细胞

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