1 |
Pages F, Mlecnik B, Marliot F, et al. International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study[J]. Lancet, 2018, 391(10135):2128-2139.
|
2 |
Bruni D, Angell HK, Galon J. The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy[J]. Nat Rev Cancer, 2020, 20(11):662-680.
|
3 |
Su H, Karin M. Multifaceted collagen-DDR1 signaling in cancer[J].Trends Cell Biol, 2024, 34(5):406-415.
|
4 |
Caligiuri G, Tuveson DA. Activated fibroblasts in cancer: Perspectives and challenges[J]. Cancer Cell, 2023, 41(3):434-449.
|
5 |
Borst R, Meyaard L, Pascoal Ramos MI. Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy[J]. J Transl Med, 2024, 22(1):382. doi: 10.1186/s12967-024-05199-3.
|
6 |
Su H, Karin M. Collagen architecture and signaling orchestrate cancer development[J]. Trends Cancer, 2023, 9(9):764-773.
|
7 |
Mei J, Cai Y, Xu R, et al. Conserved immuno-collagenic subtypes predict response to immune checkpoint blockade[J]. Cancer Commun(Lond), 2024, 44(5):554-575.
|
8 |
Fujimoto H, Yoshihara M, Rodgers R, et al. Tumor-associated fibrosis:a unique mechanism promoting ovarian cancer metastasis and peritoneal dissemination[J]. Cancer Metastasis Rev, 2024, 43(3):1037-1053.
|
9 |
Jensen C, Nissen NI, Von Arenstorff CS, et al. Serological assessment of collagen fragments and tumor fibrosis may guide immune checkpoint inhibitor therapy[J]. J Exp Clin Cancer Res, 2021, 40(1):326. doi:10.1186/s13046-021-02133-z.
|
10 |
Valkenburg KC, De Groot AE, Pienta KJ. Targeting the tumour stroma to improve cancer therapy[J]. Nat Rev Clin Oncol, 2018, 15(6):366-381.
|
11 |
Kalluri R. The biology and function of fibroblasts in cancer[J]. Nat Rev Cancer, 2016, 16(9):582-598.
|
12 |
Herzog BH, Baer JM, Borcherding N, et al. Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non-small cell lung cancer[J]. Sci Transl Med, 2023,15(699):eadh8005. doi: 10.1126/scitranslmed.adh8005.
|
13 |
Salmon H, Franciszkiewicz K, Damotte D, et al. Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors[J]. J Clin Invest, 2012, 122(3):899-910.
|
14 |
Liu Y, Yao X, Zhao Y, et al. Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells[J]. Cell Rep,2023, 42(10):113213. doi: 10.1016/j.celrep.2023.113213.
|
15 |
Xiong YX, Zhang XC, Zhu JH, et al. Collagen I-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression[J]. Cell Death Differ, 2023, 30(7):1648-1665.
|
16 |
Chen J, Ge SJ, Feng HJ, et al. KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis[J]. J Clin Transl Hepatol, 2022, 10(2):207-218.
|
17 |
Wang X, Liu S, Yu T, et al. Inhibition of integrin alphavbeta6 activation of TGF-beta attenuates tendinopathy[J]. Adv Sci (Weinh), 2022,9(11):e2104469. doi: 10.1002/advs.202104469.
|
18 |
Shi X, Chen Y, Shi M, et al. The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases[J]. Lipids Health Dis, 2024, 23(1):98.doi: 10.1186/s12944-024-02062-8.
|
19 |
Romer AMA, Thorseth ML, Madsen DH. Immune modulatory properties of collagen in cancer[J]. Front Immunol, 2021, 12:791453.doi: 10.3389/fimmu.2021.791453.
|
20 |
Kim E, Choi S, Kang B, et al. Creation of bladder assembloids mimicking tissue regeneration and cancer[J]. Nature, 2020, 588(7839):664-669.
|
21 |
Peng DH, Rodriguez BL, Diao L, et al. Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8(+) T cell exhaustion[J]. Nat Commun, 2020, 11(1):4520. doi: 10.1038/s41467-020-18298-8.
|
22 |
Gu L, Zhu Y, Lee M, et al. Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells[J]. Proc Natl Acad Sci U S A, 2023,120(19):e2300706120. doi: 10.1073/pnas.2300706120.
|
23 |
Henderson JM, Xiang MSW, Huang JC, et al. Dipeptidyl peptidase inhibition enhances CD8 T cell recruitment and activates intrahepatic inflammasome in a murine model of hepatocellular carcinoma[J].Cancers (Basel), 2021, 13(21):5495. doi: 10.3390/cancers13215495.
|
24 |
Tang P, Kirby MA, Le N, et al. Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations[J]. Light Sci Appl, 2021, 10(1):237. doi: 10.1038/s41377-021-00679-3.
|
25 |
Lambin P, Rios-Velazquez E, Leijenaar R, et al. Radiomics: extracting more information from medical images using advanced feature analysis[J]. Eur J Cancer, 2012, 48(4):441-446.
|
26 |
Li G, Li L, Li Y, et al. An MRI radiomics approach to predict survival and tumour-infiltrating macrophages in gliomas[J]. Brain, 2022,145(3):1151-1161.
|
27 |
Huang W, Jiang Y, Xiong W, et al. Noninvasive imaging of the tumor immune microenvironment correlates with response to immunotherapy in gastric cancer[J]. Nat Commun, 2022, 13(1):5095. doi: 10.1038/s41467-022-32816-w.
|
28 |
Liu HQ, Lin SY, Song YD, et al. Machine learning on MRI radiomic features: identification of molecular subtype alteration in breast cancer after neoadjuvant therapy[J]. Eur Radiol, 2022, 33(4):2965-2974.
|
29 |
Hartmann N, Giese NA, Giese T, et al. Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer[J].Clin Cancer Res, 2014, 20(13):3422-3433.
|
30 |
Johnson JD, Edman JC, Rutter WJ. A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain[J].Proc Natl Acad Sci U S A, 1993, 90(12):5677-5681.
|
31 |
Reger De Moura C, Louveau B, Jouenne F, et al. Inactivation of kindlin-3 increases human melanoma aggressiveness through the collagen-activated tyrosine kinase receptor DDR1[J]. Oncogene, 2024,43(21):1620-1630.
|
32 |
Xu H, Tan M, Hou GQ, et al. Blockade of DDR1/PYK2/ERK signaling suggesting SH2 superbinder as a novel autophagy inhibitor for pancreatic cancer[J]. Cell Death Dis, 2023, 14(12):811. doi: 10.1038/s41419-023-06344-4.
|
33 |
Sun X, Wu B, Chiang HC, et al. Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion[J]. Nature, 2021,599(7886):673-678.
|
34 |
Deng J, Kang Y, Cheng CC, et al. DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis[J]. JCI Insight,2021, 6(17):e146133. doi: 10.1172/jci.insight.146133.
|
35 |
Vijver SV, Singh A, Mommers-Elshof ETAM, et al. Collagen fragments produced in cancer mediate T cell suppression through leukocyteassociated immunoglobulin-like receptor 1[J]. Front Immunol, 2021,12:733561. doi: 10.3389/fimmu.2021.733561.
|
36 |
Huang Y, Guo DM, Bu S, et al. Systematic analysis of the prognostic significance and roles of the integrin alpha family in non-small cell lung cancers[J]. Adv Ther, 2023, 40(5):2186-2204.
|
37 |
Nicolas-Boluda A, Vaquero J, Vimeux L, et al. Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment[J]. Elife, 2021, 10:e58688. doi:10.7554/eLife.58688.
|
38 |
Horner M, Raute K, Hummel B, et al. Phytochrome-based extracellular matrix with reversibly tunable mechanical properties[J]. Adv Mater,2019, 31(12):e1806727. doi: 10.1002/adma.201806727.
|
39 |
O'connor RS, Hao X, Shen K, et al. Substrate rigidity regulates human T cell activation and proliferation[J]. J Immunol, 2012, 189(3):1330-1339.
|
40 |
Bachy S, Wu Z, Gamradt P, et al. betaig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer[J]. iScience,2022, 25(2):103758. doi: 10.1016/j.isci.2022.103758.
|
41 |
Chen M, Zhang Y, Zhou P, et al. Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-kappaB signaling pathway[J]. Bioact Mater, 2020, 5(4):880-890.
|
42 |
Erpenbeck L, Gruhn AL, Kudryasheva G, et al. Effect of adhesion and substrate elasticity on neutrophil extracellular trap formation[J]. Front Immunol, 2019, 10:2320. doi: 10.3389/fimmu.2019.02320.
|
43 |
Mai Z, Lin Y, Lin P, et al. Modulating extracellular matrix stiffness: a strategic approach to boost cancer immunotherapy[J]. Cell Death Dis,2024, 15(5):307. doi: 10.1038/s41419-024-06697-4.
|
44 |
Larue MM, Parker S, Puccini J, et al. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer[J]. Proc Natl Acad Sci U S A, 2022,119(16):e2119168119. doi: 10.1073/pnas.2119168119.
|
45 |
Tharp K M, Kersten K, Maller O, et al. Tumor-associated macrophages restrict CD8(+) T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment[J].Nat Cancer, 2024, 5(7):1045-1062.
|
46 |
Tang PC, Chung JY, Xue VW, et al. Smad3 promotes cancer-associated fibroblasts generation via macrophage-myofibroblast transition[J]. Adv Sci (Weinh), 2022, 9(1):e2101235. doi: 10.1002/advs.202101235.
|
47 |
Mei J, Cai Y, Zhu H, et al. High B7-H3 expression with low PD-L1 expression identifies armored-cold tumors in triple-negative breast cancer[J]. NPJ Breast Cancer, 2024, 10(1):11. doi: 10.1038/s41523-024-00618-6.
|
48 |
Shen B, Mei J, Xu R, et al. B7-H3 is associated with the armored-cold phenotype and predicts poor immune checkpoint blockade response in melanoma[J]. Pathol Res Pract, 2024, 256:155267. doi: 10.1016/j.prp.2024.155267.
|
49 |
Brisson BK, Stewart DC, Burgwin C, et al. Cysteine-rich domain of type III collagen N-propeptide inhibits fibroblast activation by attenuating TGFbeta signaling[J]. Matrix Biol, 2022, 109:19-33.
|
50 |
Di Martino JS, Nobre AR, Mondal C, et al. A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy[J]. Nat Cancer, 2022, 3(1):90-107.
|
51 |
Momin N, Mehta NK, Bennett NR, et al. Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy[J]. Sci Transl Med, 2019, 11(498):eaaw2614. doi:10.1126/scitranslmed.aaw2614.
|
52 |
Berestjuk I, Lecacheur M, Carminati A, et al. Targeting discoidin domain receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma[J]. EMBO Mol Med, 2022, 14(2):e11814. doi: 10.15252/emmm.201911814.
|
53 |
Xu S, Xu H, Wang W, et al. The role of collagen in cancer: from bench to bedside[J]. J Transl Med, 2019, 17(1):309. doi: 10.1186/s12967-019-2058-1.
|
54 |
Cunningham CC. Talabostat[J]. Expert Opin Investig Drugs, 2007,16(9):1459-1465.
|
55 |
Eager M, Cunningham CC, Senzer N, et al. Phase II trial of talabostat and docetaxel in advanced non-small cell lung cancer[J]. Clin Oncol (R Coll Radiol), 2009, 21(6):464-472.
|
56 |
Eager RM, Cunningham CC, Senzer NN, et al. Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma[J]. BMC Cancer, 2009, 9:263. doi: 10.1186/1471-2407-9-263.
|
57 |
Mammoto T, Jiang A, Jiang E, et al. Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression[J]. Am J Pathol,2013, 183(4):1293-1305.
|
58 |
Verginadis, Ii, Avgousti H, Monslow J, et al. A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression[J]. Nat Cell Biol, 2022,24(6):940-953.
|
59 |
Mongiat M, Andreuzzi E, Tarticchio G, et al. Extracellular Matrix, a Hard Player in Angiogenesis[J]. Int J Mol Sci, 2016, 17(11):1822. doi:10.3390/ijms17111822.
|
60 |
Hegab AE, Ozaki M, Kameyama N, et al. Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts[J]. J Pathol, 2019, 249(2):193-205.
|
61 |
Gamradt P, Thierry K, Masmoudi M, et al. Stiffness-induced cancerassociated fibroblasts are responsible for immunosuppression in a platelet-derived growth factor ligand-dependent manner[J]. PNAS Nexus, 2023, 2(12):pgad405. doi: 10.1093/pnasnexus/pgad405.
|
62 |
Mei J, Chu J, Yang K, et al. Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade[J].J Immunother Cancer, 2024, 12(9):e009327. doi: 10.1136/jitc-2024-009327.
|
63 |
Moore SC, Lee IM, Weiderpass E, et al. Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults[J]. JAMA Intern Med, 2016, 176(6):816-825.
|
64 |
Luo Z, Mei J, Wang X, et al. Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment[J]. Cell Rep, 2024, 43(9):114697.doi: 10.1016/j.celrep.2024.114697.
|