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中华细胞与干细胞杂志(电子版) ›› 2024, Vol. 14 ›› Issue (01) : 27 -29. doi: 10.3877/cma.j.issn.2095-1221.2024.01.004

病例报告

自体干细胞移植治疗POEMS综合征3例
詹卓1, 晋佩佩1, 张建敏1, 何莉1,()   
  1. 1. 430071 武汉,武汉大学中南医院血液内科
  • 收稿日期:2023-12-20 出版日期:2024-02-01
  • 通信作者: 何莉
  • Received:2023-12-20 Published:2024-02-01
引用本文:

詹卓, 晋佩佩, 张建敏, 何莉. 自体干细胞移植治疗POEMS综合征3例[J]. 中华细胞与干细胞杂志(电子版), 2024, 14(01): 27-29.

POEMS综合征临床上以多发性周围神经病、脏器肿大、内分泌障碍、M蛋白血症和皮肤病变为特征,取各个临床特征的英文首字母组合命名为POEMS综合征[1]。该疾病是以多发周围神经病变和单克隆浆细胞为主要表现的多系统损害综合征,发病率约0.3/10万,发病年龄为50 ~ 70岁[2]。该疾病是一种潜在致死性疾病,中位生存期为165个月。自体造血干细胞移植(autologous stem cell transplantation,ASCT)作为目前有望治愈POEMS综合征的方案之一[3],针对移植前治疗、移植的动员、采集干细胞方案、移植后是否需要维持治疗和并发症的预防等尚未达成共识。武汉大学中南医院血液内科收治了3例行ASCT的POEMS综合征患者,现报道如下。

1
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20
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21
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22
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23
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